Production and validation of concentrated bone marrow cells, platelet rich products and bone derivatives
This WP perform the hematological check up of patients/volunteer for blood donation enrolled by WP1, blood collection, platelet reach plasma (PRF) preparation and cryopreservation until used for injection, assignment of the patient to a randomization list, PRF distribution for treatment and proteomic analysis.
It prepares and characterizes concentrated bone marrow for WP3 and WP4 to be used in clinical and preclinical studies and for cell phenotype definition (WP4). In addition it prepares platelet concentrate and bone derivatives used respectively by WP3 and WP4 clinical studies. The synergy and high degree of interaction with the other WP, will contribute to perform a complete evaluation of both clinical and biological aspects of bone and cell preparations used for clinical trials.
Unit 1
WP Coordinator: Pier Maria Fornasari, MD, IOR
Phone: +39-051-6366216 E-mail: piermaria.fornasari@ior.it
Head of S.S.D. Immunohaematology and Transfusion Medicine and Cell and Muscoskeletal Tissue Bank
Unit Leader: Annarita Cenacchi, MD, IOR
Phone: +39-051-6366835 E-mail: annarita.cenacchi@ior.it
Coordinator of specialistic reference center in "Autotrasfusion and Hemapheresis". In the present project she will be responsible for the preparation, quality control, conservation and distribution of concentrated bone marrow cells, platelet rich products and bone derivatives