Foto della D.ssa Brunella Grigolo
Dr.ssa Brunella Grigolo
Responsabile Laboratorio RAMSES
051-6366803
051-4689945
  1. Roda A., Girotti S., Grigolo B., Ghini S. Bioluminescenza: teoria ed applicazioni analitiche. Gior.Ital. Chim. Clin. 8, 309-369,1983. NO IF
  2. Roda A., Fini A., Grigolo B., Scapini G. Routes of administration and serum levels of Methyl-14C-Cytidine Diphosphocholine. Curr. Ther. Res. 34, 6-11, 1983.
  3. Scagnolari F., Roda A., Fini A., Grigolo B. Thermodinamic features of bile salts-human serum albumin. Bioch. Bioph. Acta. 791, 274-277, 1984.
  4. Pellicciari R., Cecchetti S., Natalini B., Roda A., Grigolo B., Fini A. Bile acids with cyclopropyl-containing side chain. 1. Preparation and properties of 3Alfa7Beta-dihydroxy-22,23-methylene-5Beta-cholan-24-oic acid. J. Med. Chem. 27,746, 1984.
  5. Roda A., Girotti S., Ghini S., Grigolo B., Carrea G., Bovara R. Continuous-flow determination of primary bile acids by bioluminescence with use of nylon-immobilized bacterial enzymes. Clin. Chem. 30, 206-210, 1984.
  6. Girotti S., Roda A., Ghini S., Grigolo B., Carrea G., Bovara R. Continuous-flow analyses of NADH using bacterial bioluminescent enzymes immobilized on nylon. Anal. Letters 17, 1-12, 1984.
  7. Roda A., Girotti S., Grigolo B., Zini N., Baraldini M. Messa a punto di un dosaggio enzimatico ed immunoenzimatico bioluminescente per steroidi e molecole proteiche. Biochim. Clin. 8, 173-174, 1984.
  8. Roda A., Fini A., Fugazza R., Grigolo B. Chemical properties of bile acids: III. Bile acid structure and their solubility in water. J. Sol. Chem. Vol.14, n. 8, 595-603, 1985.
  9. Pellicciari R., Cecchetti S., Natalini B., Roda A., Grigolo B., Fini A. Bile acids with cyclopropane containing side chain: 2. Synthesis and properties of 3a,7a-dihydroxy-22,23-methylene-5ßcholan-24-oic acid (2-sulfoethyl)amide. J. Med. Chem. 28, 239, 1985.
  10. Roda A., Piacentini A.L., Grigolo B., Simoni P., Scapini G., Duranti E. Development of a sensitive enzyme immunoassay for serum I,IO-Bis- (2-hydroxyethylthio)-decane: application in the therapeutic drug monitoring. Curr. Ther. Res. Vol. 38, 500-506, 1985.
  11. Roda A., Aldini R., Grigolo B., Simoni P. Effetto della struttura degli acidi biliari sulla captazione epatica e secrezione biliare nel ratto. Biochim. Clin. 9, 575, 1985.
  12. Mazzella G., Bazzoli F., Villanova N., Grigolo B., Malavolti M. Roda A., Luzza F., Roda E. 7-ketolithocholic acid administration in man: effect on biliary lipid  composition, serum bile acid pattern and evaluation of the cholelitholytic potential. Ital. J. Gastroenterol. 18, 145-149, 1985.
  13. Aldini R., Roda A., Morselli Labate A.M., Grigolo B., Simoni P., Roda E., Barbara L. Species differences of the hepatic uptake of bile acids. Ital. J. Gastroenterol. 19, 1-64, 1986.
  14. Roda A., Girotti S., Ghini S., Piacentini A., Grigolo B. Bioluminescenza e chemiluminescenza e loro impiego ai dosaggi immunoenzimatici. Biochim. Clin. 10, 802-804, 1986.
  15. Sciarretta G., Fagiolo G., Furno A., Vicini G., Cecchetti L., Grigolo B., Verri A., Malaguti P. 75 Se HCAT test in the detection of bile acid malabsorption in functional diarrhoea and its correlation with small bowel transit. GUT, Vol. 28, n 8, 970-975, 1987.
  16. Franzone J.S., Santiano M., Reboani C., Grigolo B., Simoni P. Farmacocinetica e metabolismo epatico dell'acido ursulcolico (forma solubile dell'UDCA) nel ratto. Bollettino Chimico Farmaceutico n.7, p.289-293, 1987.
  17. Roda A., Grigolo B., Aldini R., Simoni P., Pellicciari R., Natalini B., Balducci R. Bile acids with a cyclopropyl-containing side chain. IV. Physicochemical and biological properties of the four diasteroisomers of 3,7-dihydroxy-22,23-methylene-5ß-cholan-24-oic acid. J. Lip. Res. Vol. 28, n 12, 1384-1397, 1987.
  18. Roda A., Simoni P., Grigolo B., Scapini G., Tumiatti V., Ghedini N. Acute and chronic studies of an oligomeric derivate of 1,10-bis-(2-hydroxyethylthio)decane. Curr. Ther. Res. 42, 1-7, 1987.
  19. Roda A., Grigolo B., Roda E., Simoni P., Pellicciari R., Natalini B., Fini A., Morselli Labate A.M. Quantitative relationship between bile acid structure and biliary lipid secretion in rats. J. Pharm. Sci. Vol. 27, n. 7 p. 596-605, 1988.
  20. Pellicciari R., Natalini B., Cecchetti S., Porter B., Roda A., Grigolo B., Balducci R. Bile acids with a cyclopropyl-containing side-chain. 3. Separation, identification, and properties of all four stereoisomers of 3a7ß-dihydroxy-22,23-methylene-5ß-cholan-24 oic acid. J. Med. Chem. 31,730-736, 1988.
  21. Roda A., Aldini R., Grigolo B., Simoni P., Roda E., Pellicciari R., Lenzi P.L., Natalini B. 23-methyl-3a,7ß-dihydroxy-5ß-cholan-24-oic acid: Dose-response study of biliary secretion in rat. Hepatology Vol. 8, n.6 , 1571-1576, 1988.
  22. Roda A., Fini A., Grigolo B., Simoni P., Rusticali A.G., Natalini B. Factor analysis of physicochemical properties of bile acids. Ann. Chim. 78, 15-23, 1988.
  23. Roda A., Grigolo B., Pellicciari R., Natalini B. Structure activity relationship study on natural and synthetic bile acid analogs. Dig. Dis. Sci. 34, 1-12, 1989.
  24. Roda A.,Grigolo B., Minutello A., Pellicciari R., Natalini B. Physicochemical and biological properties of natural and synthetic C-22 and C-23 hydroxylated bile acids. J Lip Res. 31, 289-298, 1990.
  25. Girotti S., Grigolo B., Ferri E., Ghini S., Carrea G., Bovara R., Roda A., Motta R., Petilino R. Bioluminescent flow sensor for the determination of L(+) Lactate. Analyst, 115, 889-894, 1990.
  26. Grigolo B., Roda A., Girotti S., Ghini S., Carrea G., Bovara R., Zini I., Grimaldi R. Real time analysis of ATP in vivo using a microdialysis and bioluminescent probe. Chimica Oggi, Vol.8, 19-21, 1990. 
  27. Mazzella G., Bazzoli F., Festi D., Ronchi M., Aldini R., Roda A., Grigolo B., Simoni P., Villanova N., Roda E. Comparative evaluation of chenodeoxycholic and ursodeoxycholic acids in obese patients. Gastroenterology, 101: 490-496, 1991.
  28. Roda A, Hrelia P, Paolini M, Calzolari M, Grigolo B, Simoni P, Aldini R.Pharmacokinetics of ursodeoxycholic acid in rat. Pharmacological research. Vol 23, issue 4,1991, 327-335.
  29. Borzì R.M., Grigolo B., Meliconi R., Fasano L., Sturani C., Fabbri M., Porstmann T., Facchini A. Elevated serum superoxide dismutase levels correlate with disease severity and neutrophil degranulation in idiopathic pulmonary fibrosis. Clin. Sci., 85: 353-359, 1993.
  30. Meliconi R., Pulsatelli L., Grigolo B., Uguccioni M., Fasano L., Fabbri M., Facchini A., Gasbarrini G. Endotelina e fibrosi polmonare. Reumatismo, 3, 189, 1993.
  31. Grigolo B., Borzì R.M., Mariani E., Monaco M.C.G., Cattini L., Porstmann T., Facchini A. Intracellular Cu/Zn superoxide dismuatese levels in T and non T cells from normal aged subjects. Mech. Ageing Dev., 73: 27-37, 1994.
  32. Grigolo B., Borzì R.M., Fasano L., Fabbri M., Meliconi R., Facchini A. Superoxide dismutases in idiopathic pulmonary fibrosis. Clin. Sci. 88: 371, 1995.
  33. Uguccioni M.G., Pulsatelli L., Grigolo B., Facchini A., Fasano L., Cinti C., Fabbri M., Gasbarrini G., Meliconi R. Endothelin-1 in idiopathic pulmonary fibrosis. J Clin. Pathol. 48, 330-334, 1995.
  34. Grigolo B., Mazzetti I., Borzì R.M., Meliconi R., Origgi L., Scorza R., Facchini A.   Comparison of different methods for the detection of autoantibodies in autoimmune diseases. Int. J. Clin. Lab. Res. 25: 205-210, 1995.
  35. Mazzetti I., Grigolo B., Borzì R.M., Meliconi R., Facchini A. Serum copper/zinc superoxide dismutase levels in patients with rheumatoid arthritis. Int. J. Clin. Lab. Res. 26:245-249, 1996.
  36. Gasbarrini A., Grigolo B., Serra M., Baldini N., Scotlandi K., Gasbarrini A., Bernardi M., Facchini A. Generation of free radicals during anoxia and reoxygenation in perfused osteoblastlike cells. Clin. Orthop. Rel. Res. 338:247-252, 1997.
  37. Grigolo B, Lisignoli G, Toneguzzi S, Mazzetti I, Facchini A. Copper/zinc superoxide dismutase expression by different osteosarcoma cell lines. Anticancer Res. 18: 1175-1180, 1998.
  38. Grigolo B, Mazzetti I, Borzì RM, Hickson ID, Fabbri M, Fasano L, Meliconi R, Facchini A. Mapping of topoisomerase II  epitopes recognized by autoantibodies in idiopathic pulmonary fibrosis. Clin. Exp. Immunol. 1998; 114:339-346.
  39. Grigolo B, Roseti L, Lisignoli G, Remiddi G, Facchini A. Expression of different chemokines by human osteosarcoma cells in response to tumour necrosis factor-. Anticancer Res, 19:3093-3098, 1999.
  40. Facchini A., Grigolo B., Roseti L., Dolzani P. Trapianto di condrociti autologhi: esperienze e opinioni a confronto. Reumatismo. Vol 51. N.2 (Suppl n.1), 1999.
  41. Grigolo B, Mazzetti I, Meliconi S, Bazzi S, Scorza R, Candela M, Gabrielli A, Facchini A. Anti-topoisomerase II autoantibodies in systemic sclerosi-association with pulmonary hypertension and HLA-B35. Clin. Exp. Immunol., 121:539-543, 2000.
  42. Gualtieri G, Ferruzzi A, Calderoni P, Andreoli I, Grigolo B, Facchini A. Autologous chondrocyte transplantation in the treatment of articular cartilage lesions of the knee. GIOT, 63:27-57, 2001.
  43. Grigolo B, Roseti L, Fiorini M, Fini M, Giavaresi G, Nicoli Aldini N, Giardino R, Facchini A. Transplantation of chondrocytes seeded on a hyaluronan derivative (Hyaff-11) into cartilage defects in rabbit. Biomaterials, 22, 2417-2424, 2001.
  44. Giannini S, MD, Buda R, Grigolo B, Vannini F. Autologous chondrocyte transplantation in osteochondral lesions of the ankle joint. Foot & Ankle, 22:513-517, 2001.
  45. Mazzetti I, Grigolo B, Pulsatelli L, Dolzani P, Silvestri T, Roseti L, Meliconi R, Facchini A. Differential role of nitric oxide and oxygen radicals in osteoarthritis and rheumatoid arthritis affected chondrocytes. Clin Sci; 101(6): 593-599,2001.
  46. Grigolo B, Lisignoli  G, Piacentini A, Fiorini  M, Gobbi P,  Mazzotti  G, Duca  M, Pavesio  A, Facchini A. Evidence for redifferentiation of human chondrocytes grown on a hyaluronan-based biomaterial–based biomaterial (HYAFF11): Molecular, Immunohistochemical and ultrastructural  analysis. Biomaterials, 23/4: 1187-1195,2002.
  47. Grigolo B., Roseti L., Neri S., Gobbi P., Jensen P., Major E.O., Facchini A. Human articular chondrocyets immortalized by HPV-16 E6 and E7 genes: Maintenance of differentiated phenotype under defined culture conditions. Ostearthritis & Cartilage 10 (11): 879-889, 2002.
  48. Grigolo B., Lisignoli G., Piacentini A., Roseti L., Fiorini M., De Franceschi L., Facchini A. Trapianto di condrociti e cellule stromali nei traumi osteoarticolari. Reumatismo, Vol. 54 N.1 Suppl. 1, 65-67, 2002.
  49. Grigolo B., Roseti L., Fiorini M., De Franceschi L., Facchini A. Applicazioni dell’ingegneria tissutale: riparazione di lesioni cartilaginee con condrociti autologhi. Reumatismo, Vol. 54 Suppl. 41, 363-370, 2002.
  50. Grigolo B., Roseti L., Fiorini M., Facchini A. Enhanced lipid peroxidation in synoviocytes from osteoarthritis patients. Journal of Rheumatology, 30(2), 345-347, 2003.
  51. Grigolo B., Roseti L., Fiorini M., Piacentini A., De Franceschi L., Facchini A. Cathepsin B as a soluble marker to monitor the phenotypic stability of engineered cartilage. Biomaterials  24/10, 1751-1757, 2003.
  52. Grigolo B., Lisignoli G., Piacentini A., Fiorini M., Roseti L., De Franceschi., L. Tognana E., Pavesio A., Facchini A. Ingegneria tissutale nel trapianto di condrociti autologhi: proprietà in vitro di un derivato dell'acido ialuronico. Chirurgia degli Organi di Movimento, LXXXVIII, 351-355, 2003.
  53. Roseti L., Grigolo B., Neri S., De Franceschi L., Jensen P., Major  E. O., Facchini A. Sviluppo di una linea di condrociti umani immortalizzati. Chirurgia degli Organi di Movimento, LXXXVIII, 363-367, 2003.
  54. Ferruzzi A, Calderoni P, Grigolo B, Gualtieri G. Autologous chondrocytes implantation: indications and results in the treatment of articular cartilage lesions of the knee. Chir Organi Mov. 2004 Apr-Jun;89(2):125-34.
  55. Grigolo B, Roseti L, De Franceschi L, Piacentini A, Cattini L, Manfredini M, Faccini R, Facchini A. Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation. J Bone Joint Surg Am. 2005 Jan;87-A(1):46-57. IF 2.487 Punti 6
  56. Cristino S, Grassi F, Toneguzzi S, Piacentini A, Grigolo B, Santi S, Riccio M, Tognana E, Facchini A, Lisignoli G. Analysis of mesenchymal stem cells grown on a three-dimensional HYAFF 11(R)-based prototype ligament scaffold.  J Biomed Mater Res A. 2005 Jun 1;73(3):275-83. 
  57. Giannini S., Buda R., Grigolo B, Vannini F. Autologous chondrocyte transplantation in osteochondral lesions of the ankle joint. Journal of Bone and Joint Surgery (Br), 87-B, Supp l.I, 2005. 
  58. Grigolo B, De Franceschi  L, Roseti L, Cattini L, Facchini A. Down regulation of degenerative cartilage molecules in chondrocytes grown on a hyluronan-based scaffold. Biomaterials. 2005 26/28:5668-5676.
  59. De Franceschi  L., Grigolo B., Roseti L., Facchini  A.,  Fini M.,  Giavaresi G., Tschon M., Giardino R. Transplantation of chondrocytes seeded on collagen-based scaffold in cartilage defects in rabbits. J Biomed Mater Res A. 2005; 1;75(3):612-622.
  60. Giannini S, Buda R, Grigolo B, Vannini F, De Franceschi L, Facchini A. The detached osteochondral fragment as a source of cells for autologous chondrocyte implantation (ACI) in the ankle joint. Osteoarthritis & Cartilage. 2005; 13: 601-607.
  61. Giannini S, Buda R, Faldini C, Vannini F, Bevoni R, Grandi G, Grigolo B, Berti L. Surgical treatment of osteochondral lesions of the talus in young active patients. J Bone Joint Surg Am. 2005;87 Suppl 2:28-41.
  62. Cristino S., Toneguzzi S., Piacentini A., Grigolo B., Cavallo C., Santi S., Riccio M., Tognana E., Frizziero A., Facchini A., Lisignoli G. Phenotype and growth analysis of mesenchymal stem cells cultured in a hylauronic acid configured ligament scaffold. Journal of Bone and Joint Surgery (Br), 87-B, Supp l.I, 2005.
  63. Grigolo B., Roseti L., Fiorini M.1, Piacentini A., De Franceschi L., Facchini A. Cathepsin B as a soluble marker to monitor the phenotypic stability of engineered cartilage. Journal of Bone and Joint Surgery (Br), 87-B, Supp l.I, 2005.
  64. Facchini A, Lisignoli G, Cristino S, Roseti L, De Franceschi L, Marconi E, Grigolo B. Human chondrocytes and mesenchymal stem cells grown onto engineered scaffold. Biorheology 2006; 43: 471-80.
  65. D. Fortuna, G. Rossi, B. Grigolo, R. Buda, A. Zati, S. Giannini, T. Bilotta, P. Mondardini, A. Crovace, L. Masotti.  Safety and efficacy of near infrared light for cartilage re-growth of deep osteochondral defetc in sheep as animal model. Osteoarthritis and Cartilage 01/2006; 14. DOI:10.1016/S1063-4584(07)60474.
  66. Roseti L, Facchini A, De Franceschi L, Marconi E, Major EO, Grigolo B. Induction of original phenotype of human immortalized chondrocytes: a quantitative gene expression analysis. Int J Mol Med. 2007: 19(1):89-96.
  67. De Franceschi L, Grigolo B, Roseti L, Marconi E, Facchini A, Buda R, Vannini F, Giannini S. Osteochondritis dissecans. Histopathology 2007 Jul;51(1):133-4.
  68. Roseti L, Buda R, Cavallo C, Desando G, Facchini A, Grigolo B. Ligament repair: A molecular and immunohistological characterization. J Appl Biomaterials & Biomechanics. Vol.5, n.3:206, 2007.
  69. Grigolo B, Roseti L, Cavallo C, Desando G, Facchini A. Rationale for the use of a hyaluronan-based scaffold to treat cartilage lesions in patient with osteoarthritis. J Appl Biomaterials & Biomechanics. Vol.5, n.3:202, 2007.
  70. De Franceschi L, Roseti L, Desando G, Facchini A, Grigolo B. A molecular and histological characterization of cartilage from patients with Morquio Syndrome. Osteoarthritis Cartilage. 2007 Jun 2.
  71. Marcacci M., Kon E., Grigolo B., Delcogliano M., Filardo G., Neri M.P. The clinician view. Osteoarthritis and Cartilage, Volume 15, Supplement 2, 2007, Pages B11-B13.
  72. Giannini S., Buda R., Vannini F., Bevoni R. and Grigolo B. Total joint reconstruction of the arthritic ankle joint using bipolar shell allograft. Osteoarthritis and Cartilage, Volume 15, Supplement 2, 2007, Page B34.
  73. Giannini S., Buda R., Vannini F., Di Caprio F., Cavallo M., Gabriele A. and Grigolo B. Osteochondral lesions of the talus: a new one-step arthroscopic procedure for the regeneration of hyaline articular cartilage. Osteoarthritis and Cartilage, Volume 15, Supplement 2, 2007, Page B74.
  74. Roseti L, Buda R, Cavallo C, Desando G, Facchini A, Grigolo B. Ligament repair: a molecular and immunohistological characterization J Biomed Mater Res A. 2007 Jan;84(1):117-27.
  75. D'Abusco AS, Calamia V, Cicione C, Grigolo B, Politi L, Scandurra R. Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes. Arthritis Res Ther. 2007;9(5).
  76. Scotto d'Abusco A, Cicione C, Calamia V, Negri R, Giordano C, Grigolo B, Politi L, Scandurra R. Glucosamine and its N-acetyl-phenylalanine derivative prevent TNF-alpha-induced transcriptional activation in human chondrocytes. Clin Exp Rheumatol. 2007 Nov-Dec;25(6):847.
  77. Giannini S, Buda R, Vannini F, Di Caprio F, Grigolo B. Arthroscopic Autologous Chondrocyte Implantation in Osteochondral Lesions of the Talus: Surgical Technique and Results. Am J Sports Med. 2008 Jan 28.
  78. Grigolo B, Lisignoli G, Desando G, Cavallo C, Marconi E, Tschon M, Giavaresi G, Fini M, Giardino R, Facchini A. Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit.  Tissue Eng Part C Methods. 2009 Dec;15(4):647-58.
  79. Giannini S, Buda R, Vannini F, Cavallo M, Grigolo B. One-step bone marrow-derived cell transplantation in talar osteochondral lesions. Clin Orthop Relat Res. 2009 Dec;467(12):3307-20. Epub 2009 May 16.
  80. Kon E, Delcogliano M, Filardo G, Pressato D, Busacca M, Grigolo B, Desando G, Marcacci M. A novel nano-composite multi-layered biomaterial for tretment of ostechondral lesions: Technique note and an early stability pilot clinical trial. Injury, 2010; Jul;41(7):693-701.
  81. Giannini S, Buda R, Grigolo B, Bevoni R, Di Caprio F, Ruffilli A, Cavallo M, Desando G, Vannini F. Bipolar fresh osteochondral allograft of the ankle. Foot Ankle Int. 2010 Jan;31(1):38-46.
  82. Cavallo C. Desando G, Facchini Andrea, Grigolo B. Chondrocytes from osteoarthritis patients express typical extracellular matrix molecules once grown onto a three dimensional scaffold. J Biomed Mater Res A. 2010 Apr;93(1):86-95.
  83. S. Giannini, R. Buda, M. Mosca, A. Ruffilli, M. Cavallo, B. Grigolo, T. Buscio, L. Ramponi and F. Vannini. Il trapianto da cadavere nella patologia degenerativa della caviglia. Archivio di Ortopedia e Reumatologia. Volume 121, Number 4, 31-34, DOI: 10.1007/s10261-010-0058-z
  84. Buda R, Vannini F, Cavallo M, Grigolo B, Cenacchi A, Giannini S. Osteochondral lesions of the knee: a new one-step repair technique with bone-marrow-derived cells. J Bone Joint Surg Am. 2010.
  85. Gobbi A, Karnatzikos G, Scotti C, Mahajan V, Mazzucco L, and Grigolo B. One-Step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-Thickness Knee Cartilage Lesions: Results at 2-Year Follow-up. Cartilage 2(3) 286-299, 2011.
  86. Cavallo C, Cuomo C, Fantini S, Ricci F, Tazzari PL, Lucarelli E, Donati D, Facchini A, Lisignoli G, Fornasari PM, Grigolo B, Moroni L. Comparison of alternative mesenchymal stem cell sources for cell banking and musculoskeletal advanced therapies. J Cell Biochem. 2011 May;112(5):1418-30
  87. Francioli S, Cavallo C, Grigolo B, Martin I, Barbero A.Engineered cartilage maturation regulates cytokine production and interleukin-1β response. Clin Orthop Relat Res. 2011 Oct;469(10):2773-84.
  88. Gabriella Teti, Carola Cavallo, Brunella Grigolo, Sandro Giannini, Andrea Facchini, Antonio Mazzotti, Mirella Falconi.
    Ultrastructural analysis of human bone marrow mesenchymal stem cells during in vitro osteogenesis and chondrogenesis Microsc Res Tech. 2011 Oct 14. doi: 10.1002/jemt.21096.
  89. Grigolo B, Desando G, Cavallo C, Zini N, Ghisu S, Facchini A. Evaluation of chondrocyte behavior in a new equine collagen scaffold useful for cartilage repair.J Biol Regul Homeost Agents. 2011 Apr-Jun;25(2 Suppl):S53-62.
  90. Grigolo B, Fiorini M, Manferdini C, Cavallo C, Gabusi E, Zini N, Dolcini L, Nicoletti A, Pressato D, Facchini A, Lisignoli G.Chemical-physical properties and in vitro cell culturing of a novel biphasic bio-mimetic scaffold for osteo-chondral tissue regeneration. J Biol Regul Homeost Agents. 2011 Apr-Jun;25(2 Suppl):S3-13.
  91. Grigolo B, Lisignoli G, Cavallo C, Desando G, Cavallo M, Vannini F, Buda R, Giannini S, Facchini A.  Hyaluronan-based scaffold for cartilage repair: from autologous chondrocytes to bone marrow concentrate cells. J Orthopedics. 2011
  92. Giannini S, Buda R, Cavallo M, Ruffilli A, Grigolo B, Fornasari PM, Vannini F. Bipolar fresh osteochondral allograft for the treatment of glenohumeral post-traumatic arthritis. Knee Surg Sports Traumatol Arthrosc. 2012 Oct;20(10):1953-7.
  93. Desando G, Cavallo C, Tschon M, Giavaresi G, Martini L, Fini M, Giardino R, Facchini A, Grigolo B. Early-Term Effect of Adult Chondrocyte Transplantation in an Osteoarthritis Animal Model. Tissue Eng Part A. 2012 Aug;18(15-16):1617-27. doi: 10.1089/ten.TEA.2011.0494. Epub 2012 Jun 25.
  94. Cavallo C, Desando G, Columbaro M. Ferrari A, Zini N, Facchini A, Grigolo B. Chondrogenic differentiation of bone marrow concentrate grown onto a hylauronan scaffold: rationale for its use in the treatment of cartilage lesions. J Biomed Mater Res A. 2012 Nov 7. doi: 10.1002/jbm.a.34460
  95. Zati A,  Desando G, Cavallo C, Buda R,. Giannini S, Fortuna D, Facchini A, Grigolo B. Treatment of human cartilage defects by means of ND:YAG laser therapy. J Biol Regul Homeost Agents. 2012 Oct-Dec;26(4):701-11.
  96. Grigolo B, Cavallo C, Desando G, Sartoni F, Facchini A. From two to one step: from autologous chondrocyte to bone marrow derived cell transplanation for the regeneration of cartilage lesions. ICRS Newsletter, 16, 2012.
  97. Desando G, Cavallo C, Sartoni F, Martini L, Parrilli A, Veronesi F, Fini M, Giardino R, Facchini A, Grigolo B.Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model.Arthritis Res Ther. 2013 Jan 29;15(1):R22.
  98. Manferdini C, Cavallo C, Grigolo B, Fiorini M, Nicoletti A, Gabusi E, Zini N, Pressato D, Facchini A, Lisignoli G. Specific inductive potential of a novel nanocomposite biomimetic biomaterial for osteochondral tissue regeneration.J Tissue Eng Regen Med. 2013 Mar 12. doi: 10.1002/term.1723.
  99. Cavallo C,  Desando G,  Cattini L. Cavallo M, Marco, Buda R, Giannini S. Facchini A. Grigolo B. Bone Marrow Concentrated Derived Cells: rationale for their use in the treatment of human osteochondral lesions. Journal of Biological regulators and homestatic agents 2013. Jan-Mar, 27 (1): 165-75.
  100. Neri S, Vannini F, Desando G, Grigolo B, Ruffilli A, Buda R, Facchini A, Giannini S. Ankle bipolar fresh osteochondral allograft survivorship and integration:transplanted tissue genetic typing and phenotypic characteristics. J Bone Joint Surg Am.2013 Oct16; 95 (20):1852-60.doi:10.2106/JBJS.L.017115.
  101. Cavallo C, Filardo G, Mariani E, Kon E, Marcacci M, Pereira Ruiz MT, Facchini A, Grigolo B. Comparison of platelet-rich plasma formulations for cartilage healing: an in vitro study. J Bone Joint Surg Am. 2014 Mar 5;96(5):423-9. doi: 10.2106/JBJS.M.00726.
  102. Giannini S, Buda R, Ruffilli A, Pagliazzi G, Ensini A, Grigolo B, Desando G, Vannini F. Failures in bipolar fresh osteochondral allograft for the treatment of end-stage knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc. 2014 Apr 4. [Epub ahead of print].
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