Chondral and osteochondral lesions still constitute a major problem in orthopaedics. These lesions can affect all the joints and can involve only the articular cartilage or also the subchondral bone. Conventional orthopaedic techniques usually applied to treat osteochondral lesions (eg: microfractures, drilling) can restore a tissue with different biomechanical properties (i.e.: fibrocartilage vs hyaline cartilage) that can lead to cartilage degeneration and bone remodeling. Regenerative medicine is a new surgical approach for treating cartilage, bone or tendon diseases using different techniques based on the combination of biomaterials with different cell populations and growth factors.
In this programme we intend to evaluate, in 4 controlled studies on patients with specific diseases affecting articular cartilage and subchondral bone (3 clinical trials and 1 longitudinal study), the treatment based on the use of growth factors, autologous cells and scaffolds.
The final REMOD event will be held on Wednesday, April 19th 2017 at the Rizzoli Orthopaedic Institute (see the program in Italian).