Few days ago, in Milan, took place the kick-off meeting of the first European register on an ultra-rare tumor, epithelioid hemangioendothelioma (EHE). The meeting was attended by Dr. Giuseppe Bianchi, orthopaedic surgeon of 3rd Orthopaedic and Traumatologic Clinic prevalently Oncologic (director prof. Davide M. Donati), and Dr. Federica Zuccheri, datamanager of Clinic III of the Rizzoli Orthopaedic Institute.