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Baldini Nicola, MD

Additional Roles


Date of Birth

Associate professor of Orthopedics, University of Bologna

Current assignment

Head, Biomedical Science and Technology Laboratory, BST Lab

Director of the Research Innovation & Technology Department (delib. n.312, 21/10/2020)

Title of qualification awarded

1981: Degree in Medicine and Surgery at the University of Bologna.

Other qualifications awarded
  • 1990: Specialization in Oncology in at the University of Bologna
  • 1987: Specialization in Orthopaedics and Traumatology at the University of Bologna
  • 2018: Diploma in Management of Health Units, University of Bologna.
Positions held
  • 2018-20: Director (ad interim), Department of Research, Innovation & Technology, IOR
  • 2019-: Head (ad interim), Laboratory for Nanobiotechnologies, IOR
  • 2017-20: Head (ad interim), Laboratory for Musculoskeletal Cell Biology, IOR
  • 2011-20: Head, Laboratory for Orthopaedic Pathophysiology and Regenerative Medicine, IOR
  • 2000-11: Deputy Director, Orthopaedic Pathophysiology and Regenerative Medicine (formerly Laboratory for Pathophysiology of Orthopaedic Implants), IOR
  • 1999: Staff surgeon, University Surgical Unit, IOR
  • 1990-99: Staff scientist, Laboratory for Oncologic Research, IOR
  • 1989-90: Fellow in Orthopaedic Surgery, Harvard Medical School & Massachusetts General Hospital, Boston (MA), USA
  • 1986: Visiting Fellow, Department of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Canada
  • 1987-89: Research fellow, Bone Tumor Center, IOR
  • 1982-87: Resident, University of Bologna, IOR
  • 1981: Visiting Fellow, Department of Surgery, Alder Hey Children’s Hospital, Liverpool, UK.
  • English: fluent.
Teaching activities
  • From 2020: Director, Master in Technologies for Precision Medicine, University of Bologna
  • From 2019: Collegio Superiore, University of Bologna
  • From 2016: Steering Committee "Health", University of Bologna
  • 2016-18: Director, Training Course in Microsurgery, University of Bologna
  • 2013-18: Director, Podiatry Training Program, University of Bologna
  • 2013-18: Visiting Professor, Kyoto Prefectural University of Medicine
  • From 2008: Associate Professor of Orthopaedics, Department of Biomedical and Neuromotor Sciences, University of Bologna
  • From 2008: Board, PhD Program in Biomedical and Neuromotor Sciences, University of Bologna.
Scientific activities
  • From 2020: Scientific Board, National Technological Cluster ALISEI-Life Sciences
  • 2019-20: President, International Society for Cancer Metabolism, ISCaM
  • From 2018: Co-coordinator, Research line "Inflammatory, infectious, degenerative and genetic diseases", IOR
  • From 2018: Steering Board, IOR
  • 2018-20: Scientific Board, IOR
  • 2013-18: Steering Committee, International Combined Orthopaedic Research Society, ICORS
  • 2009-12: Steering Committee, Forum of Italian Researchers on Mesenchymal Stem Cells, FIRST
  • 2009-12: Director, Centre for Biomedical Visualization, University of Bologna
  • 2008-12: President, European Orthopaedic Research Society, EORS
  • 2009-12: President, Italian Orthopaedic Research Society, IORS
  • From 2000: Board, Interdepartmental Centre for Cancer research "G. Prodi", University of Bologna
  • 1999-2000: President, Connective Tissue Oncology Society, CTOS.
Honorary member, Accademia Gioenia.
Marco Polo Award of Italian Science (2014).


Participation to research projects in the last 5 years:
  • 2019-23: PI AIRC project "Altered lipid metabolism as a stress reaction to acid tumour microenvironment and a driver of metastasis in osteosarcoma"
  • 2017-19: PI local unit MIUR project "Italian Regenerative Medicine Infrastructure", IRMI
  • 2018-21: PI project EC ERANet-LAC "Acid microenvironment as a target for cancer-associated bone pain"
  • 2017-22: PI local unit EC-HO2020 "Orthopaedic randomized clinical trial with expanded bone marrow MSC and bioceramics versus autograft in long bone nonunions, ORTHOUNION"
  • 2015-17: PI AIRC project "Targeting tumor-stroma interaction in sarcoma microenvironment to inhibit the development of metastases"
  • 2015-18: PI AIRC project "Targeting tumor-stroma interaction in sarcoma microenvironment to inhibit the development of metastases"
  • 2009-15: PI local unit project EC-FP7 "Regenerating bone defects using new biomedical engineering approaches, REBORNE".

Reviewer for: Acta Biomaterialia, Acta Orthopaedica, Aging, American Journal of Pathology, Autophagy, Biomaterials, Bioscience, Biotechnology and Biochemistry, BMC Research Notes, British Journal of Cancer, Cancer, Cancer Biomarkers, Cancer Letters, Cancer Management and Research, Cancers, Cell Cycle, Clinical Immunology, European Cell Materials, European Journal of Cancer, Frontiers in Oncology, Histochemical Journal, International Journal of Cancer, International Journal of Developmental Neuroscience, Journal of Bone Oncology, Journal of Experimental & Clinical Cancer Research, Journal of Cell Biology and Cell Metabolism, Journal of Clinical Oncology, Journal of Molecular Medicine, Journal of Orthopaedic Translation, Journal of Urology, Medicinal Chemistry Communications, Molecular Oncology, Nature Medicine, Neoplasia, Oncogene, Oncology, Oncotarget, Oncotargets and Therapy, PLOS ONE, Scientific Reports, Stem Cell and Development, Stem Cell International, Stem Cell Reports, The Lancet.


Author of >300 papers. Total citations: >15.000 (Scopus). H-Index: 53 (Scopus). Author of 3 books, 31 book chapters, 3 patents, 68 lectures upon invitation, >500 congress presentations.

Clinical and/or Scientific interests

Musculoskeletal oncology; pathophysiology and metabolism of bone tissue; regenerative medicine; nanostructured biomaterials; biointerfaces; visual communication of science.

Research Projects

Principal investigator nei seguenti progetti di ricerca.

Research Project
ACIDinCIBP - Acidic microenvironment as a target for cancer-associated bone pain

Acidic microenvironment as a target for cancer-associated bone pain

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